Satellite Glial Cell Markers

After subculture cells were identified by immunofluorescence labeling for three satellite glial cell specific markers.

Satellite glial cell markers.

Ginhoux f and prinz m 2015 origin of microglia. In order to differentiate between sgcs and other glial cells researchers have used markers to identify which proteins are found in different cells. Cultured cells expressed glutamine synthetase glial fibrillary acidic protein and s100β suggesting they are satellite glial cells with a purity of 95. Sgcs may be identified by the expression of several glial markers such as glutamine synthetase gs and s100β.

In a healthy nervous system astrocytes play essential roles in development regulation of blood flow by supporting endothelial cells in the blood brain barrier synaptic transmission and function and energy and metabolism by providing nutrients to neurons and synthesizing certain neurotransmitters. The most specific markers of astrocytes are gfap and s100β. The p75ntr cells were also positive for the pan glial cell markers s100 nestin and sox10 but negative for fibroblast and macrophage markers. Current topics and past controversies.

Glial cell markers glial cells commonly called neuroglia or simply glia are non neuronal cells that provide support and nutrition maintain homeostasis form myelin and participate in signal transmission in the nervous system in. From studies on rats and mice researchers have found that satellite glial cells express many neurotransmitter receptors such as muscarinic acetylcholine and erythropoietin receptors. Glutamine synthetase glial fibrillary acidic protein and s100β. Overview for cellmarker by manually curating over 100 000 published papers 4 124 entries including the cell marker information tissue type cell type cancer information and source were recorded.

Moreover they were negative for a satellite glial cell marker inwardly rectifying potassium channel kir4 1 as well as a nonmyelinating schwann cell marker glial fibrillary acidic protein. Garden ga and campbell bm 2016 glial biomarkers in human central nervous system disease. In the drgs the cell bodies of these primary afferents are anatomically surrounded by satellite glial cells sgcs forming distinct functional units. Garden ga and campbell bm 2016 glial biomarkers in human central nervous system disease.